Programming Native CRISPR Arrays for the Generation of Targeted Immunity

ABSTRACT The adaptive immune system of prokaryotes, called CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated genes), results in specific cleavage of invading nucleic acid sequences recognized by the cell’s “memory” of past encounters. Here, we exploited the...

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Bibliographic Details
Main Authors: Alexander P. Hynes, Simon J. Labrie, Sylvain Moineau
Format: article
Language:EN
Published: American Society for Microbiology 2016
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Online Access:https://doaj.org/article/e5ed4ae1150b4e7380f5f66b791592ca
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