Differential Stimulation of Pluripotent Stem Cell-Derived Human Microglia Leads to Exosomal Proteomic Changes Affecting Neurons

Microglial exosomes are an emerging communication pathway, implicated in fulfilling homeostatic microglial functions and transmitting neurodegenerative signals. Gene variants of <i>triggering receptor expressed on myeloid cells-2 (TREM2)</i> are associated with an increased risk of devel...

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Bibliographic Details
Main Authors: Anna Mallach, Johan Gobom, Charles Arber, Thomas M. Piers, John Hardy, Selina Wray, Henrik Zetterberg, Jennifer Pocock
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/e5f7dfff72ee4e26a9361a11d732053f
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