Whole-Exome Sequencing of Nasopharyngeal Carcinoma Families Reveals Novel Variants Potentially Involved in Nasopharyngeal Carcinoma

Abstract Genetic susceptibility is likely involved in nasopharyngeal carcinoma (NPC), a cancer caused by Epstein-Barr virus (EBV) infection. Understanding of genetic factors involved in NPC and how they contribute to EBV-induced carcinogenesis is limited. We conducted whole-exome capture/sequencing...

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Auteurs principaux: Guoqin Yu, Wan-Lun Hsu, Anna E. Coghill, Kelly J. Yu, Cheng-Ping Wang, Pei-Jen Lou, Zhiwei Liu, Kristie Jones, Aurelie Vogt, Mingyi Wang, Sam M. Mbulaiteye, Hao-Hui Chen, Joseph Boland, Meredith Yeager, Scott R. Diehl, Chien-Jen Chen, Allan Hildesheim, Alisa M. Goldstein
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/e5fb76f62f6e481fa602857aaba4b9ad
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