Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin

Abstract Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruptions to the intestinal epithelial barrier and translocation of bacteria, resulting in inflammation, are common in colitis. The mechanisms underlying epithelial barrier dysfunction or regulation...

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Autores principales: Chaithanya Chelakkot, Jaewang Ghim, Nirmal Rajasekaran, Jong-Sun Choi, Jung-Hwan Kim, Myoung Ho Jang, Young Kee Shin, Pann-Ghill Suh, Sung Ho Ryu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e627bc7f4f0645b6bc20709220d51531
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