Genome-Wide siRNA Screen Identifies Complementary Signaling Pathways Involved in <italic toggle="yes">Listeria</italic> Infection and Reveals Different Actin Nucleation Mechanisms during <italic toggle="yes">Listeria</italic> Cell Invasion and Actin Comet Tail Formation
ABSTRACT Listeria monocytogenes enters nonphagocytic cells by a receptor-mediated mechanism that is dependent on a clathrin-based molecular machinery and actin rearrangements. Bacterial intra- and intercellular movements are also actin dependent and rely on the actin nucleating Arp2/3 complex, which...
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Auteurs principaux: | Andreas Kühbacher, Mario Emmenlauer, Pauli Rämo, Natasha Kafai, Christoph Dehio, Pascale Cossart, Javier Pizarro-Cerdá |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2015
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Accès en ligne: | https://doaj.org/article/e684d7ac5e7c46c8bae6ac0cdf53c382 |
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