Neonatal administration of a subanaesthetic dose of JM-1232(−) in mice results in no behavioural deficits in adulthood

Abstract In animal models, neonatal exposure of general anaesthetics significantly increases apoptosis in the brain, resulting in persistent behavioural deficits later in adulthood. Consequently, there is growing concern about the use of general anaesthetics in obstetric and paediatric practice. JM-...

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Autores principales: Koji Iwanaga, Yasushi Satoh, Ryosuke Akai, Toshiaki Ishizuka, Tomiei Kazama, Takehiko Ikeda
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e6af7627e5cb46d1be1b4146f12f9228
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