Mechanical strain regulates osteoblast proliferation through integrin-mediated ERK activation.

Mechanical strain plays a critical role in the proliferation, differentiation and maturation of bone cells. As mechanical receptor cells, osteoblasts perceive and respond to stress force, such as those associated with compression, strain and shear stress. However, the underlying molecular mechanisms...

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Auteurs principaux: Yu-xian Yan, Yuan-wei Gong, Yong Guo, Qi Lv, Chun Guo, Yan Zhuang, Yuan Zhang, Ruixin Li, Xi-zheng Zhang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Q
Accès en ligne:https://doaj.org/article/e6bb730e82ea44008eeda1bfb565b212
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