Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528

Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. Here authors study several dynein cofactors and their role in force adaptation of dynein during lipid droplet, lysosomal, and mitochondrial transport.

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Auteurs principaux: Dail E. Chapman, Babu J. N. Reddy, Bunchhin Huy, Matthew J. Bovyn, Stephen John S. Cruz, Zahraa M. Al-Shammari, Han Han, Wenqi Wang, Deanna S. Smith, Steven P. Gross
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/e6ccfec8ba164322ae51709ecaf1ad14
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