Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528

Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. Here authors study several dynein cofactors and their role in force adaptation of dynein during lipid droplet, lysosomal, and mitochondrial transport.

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Autores principales: Dail E. Chapman, Babu J. N. Reddy, Bunchhin Huy, Matthew J. Bovyn, Stephen John S. Cruz, Zahraa M. Al-Shammari, Han Han, Wenqi Wang, Deanna S. Smith, Steven P. Gross
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e6ccfec8ba164322ae51709ecaf1ad14
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spelling oai:doaj.org-article:e6ccfec8ba164322ae51709ecaf1ad142021-12-02T17:33:23ZRegulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA052810.1038/s41467-018-08110-z2041-1723https://doaj.org/article/e6ccfec8ba164322ae51709ecaf1ad142019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08110-zhttps://doaj.org/toc/2041-1723Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. Here authors study several dynein cofactors and their role in force adaptation of dynein during lipid droplet, lysosomal, and mitochondrial transport.Dail E. ChapmanBabu J. N. ReddyBunchhin HuyMatthew J. BovynStephen John S. CruzZahraa M. Al-ShammariHan HanWenqi WangDeanna S. SmithSteven P. GrossNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dail E. Chapman
Babu J. N. Reddy
Bunchhin Huy
Matthew J. Bovyn
Stephen John S. Cruz
Zahraa M. Al-Shammari
Han Han
Wenqi Wang
Deanna S. Smith
Steven P. Gross
Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
description Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. Here authors study several dynein cofactors and their role in force adaptation of dynein during lipid droplet, lysosomal, and mitochondrial transport.
format article
author Dail E. Chapman
Babu J. N. Reddy
Bunchhin Huy
Matthew J. Bovyn
Stephen John S. Cruz
Zahraa M. Al-Shammari
Han Han
Wenqi Wang
Deanna S. Smith
Steven P. Gross
author_facet Dail E. Chapman
Babu J. N. Reddy
Bunchhin Huy
Matthew J. Bovyn
Stephen John S. Cruz
Zahraa M. Al-Shammari
Han Han
Wenqi Wang
Deanna S. Smith
Steven P. Gross
author_sort Dail E. Chapman
title Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
title_short Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
title_full Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
title_fullStr Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
title_full_unstemmed Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528
title_sort regulation of in vivo dynein force production by cdk5 and 14-3-3ε and kiaa0528
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e6ccfec8ba164322ae51709ecaf1ad14
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