Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system

G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.

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Autores principales: Nathan H. Kipniss, P. C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e70108db447c4b069358555aee209a1d
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