Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system

G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.

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Autores principales: Nathan H. Kipniss, P. C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e70108db447c4b069358555aee209a1d
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spelling oai:doaj.org-article:e70108db447c4b069358555aee209a1d2021-12-02T14:41:08ZEngineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system10.1038/s41467-017-02075-12041-1723https://doaj.org/article/e70108db447c4b069358555aee209a1d2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02075-1https://doaj.org/toc/2041-1723G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.Nathan H. KipnissP. C. Dave P. DingalTimothy R. AbbottYuchen GaoHaifeng WangAntonia A. DominguezLouai LabaniehLei S. QiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nathan H. Kipniss
P. C. Dave P. Dingal
Timothy R. Abbott
Yuchen Gao
Haifeng Wang
Antonia A. Dominguez
Louai Labanieh
Lei S. Qi
Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
description G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.
format article
author Nathan H. Kipniss
P. C. Dave P. Dingal
Timothy R. Abbott
Yuchen Gao
Haifeng Wang
Antonia A. Dominguez
Louai Labanieh
Lei S. Qi
author_facet Nathan H. Kipniss
P. C. Dave P. Dingal
Timothy R. Abbott
Yuchen Gao
Haifeng Wang
Antonia A. Dominguez
Louai Labanieh
Lei S. Qi
author_sort Nathan H. Kipniss
title Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
title_short Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
title_full Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
title_fullStr Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
title_full_unstemmed Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system
title_sort engineering cell sensing and responses using a gpcr-coupled crispr-cas system
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e70108db447c4b069358555aee209a1d
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