Intracellular Water Lifetime as a Tumor Biomarker to Monitor Doxorubicin Treatment via FFC-Relaxometry in a Breast Cancer Model

This study aims to explore whether the water exchange rate constants in tumor cells can act as a hallmark of pathology status and a reporter of therapeutic outcomes. It has been shown, using 4T1 cell cultures and murine allografts, that an early assessment of the therapeutic effect of doxorubicin ca...

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Bibliographic Details
Main Authors: Maria Rosaria Ruggiero, Simona Baroni, Valeria Bitonto, Roberto Ruiu, Smeralda Rapisarda, Silvio Aime, Simonetta Geninatti Crich
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/e704e27b3e7d4c89a99602ff6b0019b6
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