Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020
Background: In August 2020, an outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 occurred in the United Kingdom. Whole genome sequencing revealed that these cases formed a genetically distinct cluster. Methods: Hypotheses generated from case interviews were tested in analytical studi...
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Elsevier
2021
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oai:doaj.org-article:e73337324a874f5cb3b8df14db678b352021-11-06T04:21:39ZOutbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 20201201-971210.1016/j.ijid.2021.04.001https://doaj.org/article/e73337324a874f5cb3b8df14db678b352021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S120197122100312Xhttps://doaj.org/toc/1201-9712Background: In August 2020, an outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 occurred in the United Kingdom. Whole genome sequencing revealed that these cases formed a genetically distinct cluster. Methods: Hypotheses generated from case interviews were tested in analytical studies, and results informed environmental sampling and food chain analysis. A case–case study used non-outbreak ‘comparison’ STEC cases; a case–control study used a market research panel to recruit controls. Results: A total of 36 cases were identified; all cases reported symptom onset between August 3 and August 16, 2020. The majority of cases (83%) resided in the Midlands region of England and in Wales. A high proportion of cases reported eating out, with one fast-food restaurant chain mentioned by 64% (n = 23) of cases. Both the case–case study (adjusted odds ratio (aOR) 31.8, 95% confidence interval (CI) 1.6–624.9) and the case–control study (aOR 9.19, 95% CI 1.0–82.8) revealed statistically significant results, showing that the consumption of a specific fast-food product was independently associated with infection. Conclusions: Consumption of a specific fast-food product was a likely cause of this outbreak. The only ingredient specific to the product was cucumbers. The supply of cucumbers was immediately halted, and no further cases have been identified.Ranya MulchandaniClare BrehmerSaira ButtBhavita VishramMelissa HarrisonElizabeth MarchantSimon FerrisFrieda JorgensenRobert SmithGauri GodboleClaire JenkinsTimothy J. DallmanNeville Q. VerlanderNick PhinDan TodkillSaheer GharbiaJeremy HawkerElsevierarticleInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 110, Iss , Pp S62-S68 (2021) |
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DOAJ |
| collection |
DOAJ |
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EN |
| topic |
Infectious and parasitic diseases RC109-216 |
| spellingShingle |
Infectious and parasitic diseases RC109-216 Ranya Mulchandani Clare Brehmer Saira Butt Bhavita Vishram Melissa Harrison Elizabeth Marchant Simon Ferris Frieda Jorgensen Robert Smith Gauri Godbole Claire Jenkins Timothy J. Dallman Neville Q. Verlander Nick Phin Dan Todkill Saheer Gharbia Jeremy Hawker Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| description |
Background: In August 2020, an outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 occurred in the United Kingdom. Whole genome sequencing revealed that these cases formed a genetically distinct cluster. Methods: Hypotheses generated from case interviews were tested in analytical studies, and results informed environmental sampling and food chain analysis. A case–case study used non-outbreak ‘comparison’ STEC cases; a case–control study used a market research panel to recruit controls. Results: A total of 36 cases were identified; all cases reported symptom onset between August 3 and August 16, 2020. The majority of cases (83%) resided in the Midlands region of England and in Wales. A high proportion of cases reported eating out, with one fast-food restaurant chain mentioned by 64% (n = 23) of cases. Both the case–case study (adjusted odds ratio (aOR) 31.8, 95% confidence interval (CI) 1.6–624.9) and the case–control study (aOR 9.19, 95% CI 1.0–82.8) revealed statistically significant results, showing that the consumption of a specific fast-food product was independently associated with infection. Conclusions: Consumption of a specific fast-food product was a likely cause of this outbreak. The only ingredient specific to the product was cucumbers. The supply of cucumbers was immediately halted, and no further cases have been identified. |
| format |
article |
| author |
Ranya Mulchandani Clare Brehmer Saira Butt Bhavita Vishram Melissa Harrison Elizabeth Marchant Simon Ferris Frieda Jorgensen Robert Smith Gauri Godbole Claire Jenkins Timothy J. Dallman Neville Q. Verlander Nick Phin Dan Todkill Saheer Gharbia Jeremy Hawker |
| author_facet |
Ranya Mulchandani Clare Brehmer Saira Butt Bhavita Vishram Melissa Harrison Elizabeth Marchant Simon Ferris Frieda Jorgensen Robert Smith Gauri Godbole Claire Jenkins Timothy J. Dallman Neville Q. Verlander Nick Phin Dan Todkill Saheer Gharbia Jeremy Hawker |
| author_sort |
Ranya Mulchandani |
| title |
Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| title_short |
Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| title_full |
Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| title_fullStr |
Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| title_full_unstemmed |
Outbreak of Shiga toxin-producing Escherichia coli O157 linked with consumption of a fast-food product containing imported cucumbers, United Kingdom, August 2020 |
| title_sort |
outbreak of shiga toxin-producing escherichia coli o157 linked with consumption of a fast-food product containing imported cucumbers, united kingdom, august 2020 |
| publisher |
Elsevier |
| publishDate |
2021 |
| url |
https://doaj.org/article/e73337324a874f5cb3b8df14db678b35 |
| work_keys_str_mv |
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