Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.

Eosinophils function contributes to human allergic and autoimmune diseases, many of which currently lack curative treatment. Development of more effective treatments for eosinophil-related diseases requires expanded understanding of eosinophil signaling and biology. Cell signaling requires integrati...

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Autores principales: Mandy E Burnham, Stephane Esnault, Elon C Roti Roti, Mary E Bates, Paul J Bertics, Loren C Denlinger
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/e73653c0498c413a82e5d4522509eddc
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