The presence of extra chromosomes leads to genomic instability
One of the hallmarks of cancer cells is aneuploidy, however the molecular effects are poorly understood. Here the authors show that trisomic and tetrasomic cells display increased genomic instability and reduced levels of the helicase MCM2-7.
Enregistré dans:
| Auteurs principaux: | , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/e73b828e409d4bfbb86d27e03daef072 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|