Cytochrome C oxidase Inhibition and Cold Plasma-derived Oxidants Synergize in Melanoma Cell Death Induction

Abstract Despite striking advances in the treatment of metastasized melanoma, the disease is often still fatal. Attention is therefore paid towards combinational regimens. Oxidants endogenously produced in mitochondria are currently targeted in pre-clinical and clinical studies. Cytotoxic synergism...

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Autores principales: Rajesh Kumar Gandhirajan, Katrin Rödder, Yana Bodnar, Gabriella Pasqual-Melo, Steffen Emmert, Corinne E. Griguer, Klaus-Dieter Weltmann, Sander Bekeschus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e7765252a4bf4fd98c1c2fb12bede776
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