Response of Merkel cell polyomavirus-positive merkel cell carcinoma xenografts to a survivin inhibitor.
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer associated with high mortality. Merkel cell polyomavirus (MCV), discovered in 2008, is associated with ~80% of MCC. The MCV large tumor (LT) oncoprotein upregulates the cellular oncoprotein survivin through its conserved retinoblastoma prot...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
|
| Subjects: | |
| Online Access: | https://doaj.org/article/e7909d6eac544daa993c3a34efd7e948 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|