Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
<h4>Background</h4>Familial hypercholesterolemia (FH) is an autosomal codominant disorder caused by mutations in the low-density lipoprotein receptor (LDLR) gene. Homozygous FH patients (hoFH) have severe hypercholesterolemia leading to life threatening atherosclerosis in childhood and a...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/e79587d53a7b4820b632c5dfd2a0f483 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|