Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.
<h4>Background</h4>Familial hypercholesterolemia (FH) is an autosomal codominant disorder caused by mutations in the low-density lipoprotein receptor (LDLR) gene. Homozygous FH patients (hoFH) have severe hypercholesterolemia leading to life threatening atherosclerosis in childhood and a...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2010
|
| Subjects: | |
| Online Access: | https://doaj.org/article/e79587d53a7b4820b632c5dfd2a0f483 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!