HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

Histone deacetylases, such as HDAC3, have been shown to alter cellular metabolism in various tissues. Here the authors show that HDAC3 regulates WAT metabolism by activating a futile cycle of fatty acid synthesis and oxidation, which supports WAT browning.

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Detalles Bibliográficos
Autores principales: Alessandra Ferrari, Raffaella Longo, Erika Fiorino, Rui Silva, Nico Mitro, Gaia Cermenati, Federica Gilardi, Béatrice Desvergne, Annapaola Andolfo, Cinzia Magagnotti, Donatella Caruso, Emma De Fabiani, Scott W. Hiebert, Maurizio Crestani
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/e79e6f94830242d2a35e5f6ab7dac919
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