Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology

Abstract Interferons (IFNs) are key cytokines involved in alerting the immune system to viral infection. After IFN stimulation, cellular transcriptional profile critically changes, leading to the expression of several IFN stimulated genes (ISGs) that exert a wide variety of antiviral activities. Des...

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Autores principales: Cristina Cheroni, Lara Manganaro, Lorena Donnici, Valeria Bevilacqua, Raoul J. P. Bonnal, Riccardo L. Rossi, Raffaele De Francesco
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e7ea4f5c876b42c19f3dfa4679c5eca3
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