Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology
Abstract Interferons (IFNs) are key cytokines involved in alerting the immune system to viral infection. After IFN stimulation, cellular transcriptional profile critically changes, leading to the expression of several IFN stimulated genes (ISGs) that exert a wide variety of antiviral activities. Des...
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Main Authors: | Cristina Cheroni, Lara Manganaro, Lorena Donnici, Valeria Bevilacqua, Raoul J. P. Bonnal, Riccardo L. Rossi, Raffaele De Francesco |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/e7ea4f5c876b42c19f3dfa4679c5eca3 |
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