Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology

Abstract Interferons (IFNs) are key cytokines involved in alerting the immune system to viral infection. After IFN stimulation, cellular transcriptional profile critically changes, leading to the expression of several IFN stimulated genes (ISGs) that exert a wide variety of antiviral activities. Des...

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Bibliographic Details
Main Authors: Cristina Cheroni, Lara Manganaro, Lorena Donnici, Valeria Bevilacqua, Raoul J. P. Bonnal, Riccardo L. Rossi, Raffaele De Francesco
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/e7ea4f5c876b42c19f3dfa4679c5eca3
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