Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy

Since the discovery of mechanically planar chiral rotaxanes and topologically chiral catenanes, their asymmetric synthesis has been a long-standing challenge. Here, the authors report enantioselective preparation of mechanically planar chiral rotaxanes with up to 99.9% ee in 29% yield.

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Autores principales: Ayumi Imayoshi, Bhatraju Vasantha Lakshmi, Yoshihiro Ueda, Tomoyuki Yoshimura, Aki Matayoshi, Takumi Furuta, Takeo Kawabata
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e8236e10a064472da76bf6e8c01ff2d3
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