Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy

Since the discovery of mechanically planar chiral rotaxanes and topologically chiral catenanes, their asymmetric synthesis has been a long-standing challenge. Here, the authors report enantioselective preparation of mechanically planar chiral rotaxanes with up to 99.9% ee in 29% yield.

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Main Authors:	Ayumi Imayoshi, Bhatraju Vasantha Lakshmi, Yoshihiro Ueda, Tomoyuki Yoshimura, Aki Matayoshi, Takumi Furuta, Takeo Kawabata
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/e8236e10a064472da76bf6e8c01ff2d3
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spelling	oai:doaj.org-article:e8236e10a064472da76bf6e8c01ff2d32021-12-02T14:01:14ZEnantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy10.1038/s41467-020-20372-02041-1723https://doaj.org/article/e8236e10a064472da76bf6e8c01ff2d32021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20372-0https://doaj.org/toc/2041-1723Since the discovery of mechanically planar chiral rotaxanes and topologically chiral catenanes, their asymmetric synthesis has been a long-standing challenge. Here, the authors report enantioselective preparation of mechanically planar chiral rotaxanes with up to 99.9% ee in 29% yield.Ayumi ImayoshiBhatraju Vasantha LakshmiYoshihiro UedaTomoyuki YoshimuraAki MatayoshiTakumi FurutaTakeo KawabataNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ayumi Imayoshi Bhatraju Vasantha Lakshmi Yoshihiro Ueda Tomoyuki Yoshimura Aki Matayoshi Takumi Furuta Takeo Kawabata Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
description	Since the discovery of mechanically planar chiral rotaxanes and topologically chiral catenanes, their asymmetric synthesis has been a long-standing challenge. Here, the authors report enantioselective preparation of mechanically planar chiral rotaxanes with up to 99.9% ee in 29% yield.
format	article
author	Ayumi Imayoshi Bhatraju Vasantha Lakshmi Yoshihiro Ueda Tomoyuki Yoshimura Aki Matayoshi Takumi Furuta Takeo Kawabata
author_facet	Ayumi Imayoshi Bhatraju Vasantha Lakshmi Yoshihiro Ueda Tomoyuki Yoshimura Aki Matayoshi Takumi Furuta Takeo Kawabata
author_sort	Ayumi Imayoshi
title	Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
title_short	Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
title_full	Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
title_fullStr	Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
title_full_unstemmed	Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
title_sort	enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e8236e10a064472da76bf6e8c01ff2d3
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Enantioselective preparation of mechanically planar chiral rotaxanes by kinetic resolution strategy

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