Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes

Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has been observed within the nuclei of neurons, but there i...

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Auteurs principaux: Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
tau
Accès en ligne:https://doaj.org/article/e82630aa9dc645a094f19b3dcebd97b6
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