Tau Modulates mRNA Transcription, Alternative Polyadenylation Profiles of hnRNPs, Chromatin Remodeling and Spliceosome Complexes
Tau protein is a known contributor in several neurodegenerative diseases, including Alzheimer’s disease (AD) and frontotemporal dementia (FTD). It is well-established that tau forms pathological aggregates and fibrils in these diseases. Tau has been observed within the nuclei of neurons, but there i...
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Auteurs principaux: | Mauro Montalbano, Elizabeth Jaworski, Stephanie Garcia, Anna Ellsworth, Salome McAllen, Andrew Routh, Rakez Kayed |
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Format: | article |
Langue: | EN |
Publié: |
Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/e82630aa9dc645a094f19b3dcebd97b6 |
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