Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence

Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence

Abstract Oesophageal cancer (OC) has high mortality. This study aims at determining the feasibility of liquid biopsies for genomic profiling in early stage OC, comparing two different technologies for mutational analysis in circulating cell -free DNA (ccfDNA) and evaluating the clinical impact of th...

Full description

Saved in:
Bibliographic Details
Main Authors: Helen Pasternack, Jana Fassunke, Patrick Sven Plum, Seung-Hun Chon, Daniel Alexander Hescheler, Asmae Gassa, Sabine Merkelbach-Bruse, Christiane Josephine Bruns, Sven Perner, Michael Hallek, Reinhard Büttner, Elfriede Bollschweiler, Arnulf Heinrich Hölscher, Alexander Quaas, Thomas Zander, Jonathan Weiss, Hakan Alakus
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Somatic Alterations
Primary Stage
ccfDNA
Simultaneous Blood Samples
Post-surgical Outcomes
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e866facbb8674b04bb198aaa07a3731b
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items