Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of <italic toggle="yes">Klebsiella pneumoniae</italic> Carbapenemase-Carrying Plasmids
ABSTRACT The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and colistin. Large, complex resistance plasmi...
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Autores principales: | Michelle M. C. Buckner, Howard T. H. Saw, Rachael N. Osagie, Alan McNally, Vito Ricci, Matthew E. Wand, Neil Woodford, Alasdair Ivens, Mark A. Webber, Laura J. V. Piddock |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/e89e885bb47942509854170b9bff404f |
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