Binding Heterogeneity of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1

ABSTRACT Cerebral malaria is a severe neurological complication associated with sequestration of Plasmodium falciparum-infected erythrocytes (IE) in the brain microvasculature, but the specific binding interactions remain under debate. Here, we have generated an engineered three-dimensional (3D) hum...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Maria Bernabeu, Celina Gunnarsson, Maria Vishnyakova, Caitlin C. Howard, Ryan J. Nagao, Marion Avril, Terrie E. Taylor, Karl B. Seydel, Ying Zheng, Joseph D. Smith
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://doaj.org/article/e8baabff64bb490f8a669a8d2a19155f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!