Complex formation between NheB and NheC is necessary to induce cytotoxic activity by the three-component Bacillus cereus Nhe enterotoxin.
The nonhemolytic enterotoxin (Nhe) is known as a major pathogenicity factor for the diarrheal type of food poisoning caused by Bacillus cereus. The Nhe complex consists of NheA, NheB and NheC, all of them required to reach maximum cytotoxicity following a specific binding order on cell membranes. He...
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Main Authors: | Uta Heilkenbrinker, Richard Dietrich, Andrea Didier, Kui Zhu, Toril Lindbäck, Per Einar Granum, Erwin Märtlbauer |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/e8c80addb8ab4fb29eb4e445cce559aa |
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