A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma

A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma

A sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) system was developed and fully validated for the simultaneous determination of ephedrine and pseudoephedrine in human plasma after oral administration of the herbal prescription Ojeok-san (OJS); 2-phenylethylamine...

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Détails bibliographiques
Auteurs principaux: Sooyoung Lee, Wang-Seob Shim, Heejo Yoo, Sanghee Choi, Jiyoung Yoon, Kwang-Young Lee, Eun-Kyoung Chung, Byung-Cheol Lee, Sung-Vin Yim, Bo-Hyung Kim, Kyung-Tae Lee
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
ephedrine
pseudoephedrine
liquid chromatography-tandem mass spectrometry
bioanalytical method validation
pharmacokinetics
healthy volunteers
Organic chemistry
QD241-441
Accès en ligne:https://doaj.org/article/e90ab1bdd10343f495d7e182cba62878
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https://doaj.org/article/e90ab1bdd10343f495d7e182cba62878

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