A highly potent ruthenium(II)-sonosensitizer and sonocatalyst for in vivo sonotherapy

Sonodynamic therapy has therapeutic promise due to its safety and good tissue penetration, but is currently bottlenecked due to a lack of efficient and safe sonosensitizers. Here the authors show that [Ru(bpy)3]2+ can produce singlet oxygen and sonooxidize NADH in deep tissue, and destroy mouse tumo...

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Bibliographic Details
Main Authors: Chao Liang, Jiaen Xie, Shuangling Luo, Can Huang, Qianling Zhang, Huaiyi Huang, Pingyu Zhang
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/e91c50b481d241a5a03c46be3e14769c
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