BHX, a novel pyrazoline derivative, inhibits breast cancer cell invasion by reversing the epithelial-mesenchymal transition and down-regulating Wnt/β-catenin signalling

Abstract The novel pyrazoline derivative, BHX, has recently been shown to exhibit potent anti-tumour activity by blocking the Wnt/β-catenin signalling pathway. However, its effect on breast cancer growth and invasion are unknown. Our results show that BHX suppresses MDA-MB-231 cell viability and col...

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Bibliographic Details
Main Authors: Hanmei Bao, Qing Zhang, Zhongling Zhu, Hui Xu, Fengxia Ding, Meisa Wang, Shuangshuang Du, Yibo Du, Zhao Yan
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/e91f0d86c1af44df9ee4ee4d67e260a7
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