BHX, a novel pyrazoline derivative, inhibits breast cancer cell invasion by reversing the epithelial-mesenchymal transition and down-regulating Wnt/β-catenin signalling
Abstract The novel pyrazoline derivative, BHX, has recently been shown to exhibit potent anti-tumour activity by blocking the Wnt/β-catenin signalling pathway. However, its effect on breast cancer growth and invasion are unknown. Our results show that BHX suppresses MDA-MB-231 cell viability and col...
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Autores principales: | Hanmei Bao, Qing Zhang, Zhongling Zhu, Hui Xu, Fengxia Ding, Meisa Wang, Shuangshuang Du, Yibo Du, Zhao Yan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/e91f0d86c1af44df9ee4ee4d67e260a7 |
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