MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors

MicroRNAs promote skeletal muscle differentiation of mesodermal iPSC-derived progenitors

Mesodermal iPSC-derived progenitors (MiPs) can regenerate both skeletal and cardiac muscle. Here, the authors show that a microRNA cocktail stimulates skeletal muscle differentiation and that human MiPs can engraft into striated muscle in mice.

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Auteurs principaux: Giorgia Giacomazzi, Bryan Holvoet, Sander Trenson, Ellen Caluwé, Bojana Kravic, Hanne Grosemans, Álvaro Cortés-Calabuig, Christophe M. Deroose, Danny Huylebroeck, Said Hashemolhosseini, Stefan Janssens, Elizabeth McNally, Mattia Quattrocelli, Maurilio Sampaolesi
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/e92068e1fa5d401cb076a3ec19008468
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Internet

https://doaj.org/article/e92068e1fa5d401cb076a3ec19008468

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