Structural basis for plazomicin antibiotic action and resistance

Golkar, Bassenden et al. report two structures of the latest generation aminoglycoside antibiotic plazomicin in complex with the bacterial 70S ribosome as well as in complex with AAC(2’)-la acetyltransferase, an antibiotic modification enzyme (AME). Their study can be useful in the development of ne...

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Autores principales: Tolou Golkar, Angelia V. Bassenden, Krishnagopal Maiti, Dev P. Arya, T. Martin Schmeing, Albert M. Berghuis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e920b775f2c646bfaee3171a047210be
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