Induction of Immune Tolerance in Islet Transplantation Using Apoptotic Donor Leukocytes
Allogeneic islet transplantation has become an effective treatment option for severe Type 1 diabetes with intractable impaired awareness due to hypoglycemic events. Although current immunosuppressive protocols effectively prevent the acute rejection associated with initial T cell activation in recip...
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Main Authors: | Naoya Sato, Shigeru Marubashi |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/e9218a7a69e449feaf66c1cfcf1f39c7 |
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