Genetic variation in the Plasmodium falciparum circumsporozoite protein in India and its relevance to RTS,S malaria vaccine.

Genetic variation in the Plasmodium falciparum circumsporozoite protein in India and its relevance to RTS,S malaria vaccine.

RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region and the complete C-terminal T cell epitope region (Th2R and Th3R) of the circumsporozoite protein (CSP). Since natu...

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Main Authors: Mohammad Zeeshan, Mohammad Tauqeer Alam, Sumiti Vinayak, Hema Bora, Rupesh Kumar Tyagi, Mohd Shoeb Alam, Vandana Choudhary, Pooja Mittra, Vanshika Lumb, Praveen Kumar Bharti, Venkatachalam Udhayakumar, Neeru Singh, Vidhan Jain, Pushpendra Pal Singh, Yagya Dutta Sharma
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/e93356ca7e9d4fa895a299418020c96b
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https://doaj.org/article/e93356ca7e9d4fa895a299418020c96b

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