Quantification of protein copy number in yeast: the NAD+ metabolome.

Saccharomyces cerevisiae is calorie-restricted by lowering glucose from 2% to 0.5%. Under low glucose conditions, replicative lifespan is extended in a manner that depends on the NAD+-dependent protein lysine deacetylase Sir2 and NAD+ salvage enzymes. Because NAD+ is required for glucose utilization...

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Auteurs principaux: Szu-Chieh Mei, Charles Brenner
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/e95f003c144a47c0a83cde7bb1000ecb
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