The complete structure of an activated open sodium channel

Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.

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Autores principales: Altin Sula, Jennifer Booker, Leo C. T. Ng, Claire E. Naylor, Paul G. DeCaen, B. A. Wallace
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
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