The complete structure of an activated open sodium channel

Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.

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Autores principales:	Altin Sula, Jennifer Booker, Leo C. T. Ng, Claire E. Naylor, Paul G. DeCaen, B. A. Wallace
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
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spelling	oai:doaj.org-article:e9790fdf9aa34bac8509eea7e2e8e3c12021-12-02T17:06:21ZThe complete structure of an activated open sodium channel10.1038/ncomms142052041-1723https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c12017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14205https://doaj.org/toc/2041-1723Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.Altin SulaJennifer BookerLeo C. T. NgClaire E. NaylorPaul G. DeCaenB. A. WallaceNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Altin Sula Jennifer Booker Leo C. T. Ng Claire E. Naylor Paul G. DeCaen B. A. Wallace The complete structure of an activated open sodium channel
description	Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.
format	article
author	Altin Sula Jennifer Booker Leo C. T. Ng Claire E. Naylor Paul G. DeCaen B. A. Wallace
author_facet	Altin Sula Jennifer Booker Leo C. T. Ng Claire E. Naylor Paul G. DeCaen B. A. Wallace
author_sort	Altin Sula
title	The complete structure of an activated open sodium channel
title_short	The complete structure of an activated open sodium channel
title_full	The complete structure of an activated open sodium channel
title_fullStr	The complete structure of an activated open sodium channel
title_full_unstemmed	The complete structure of an activated open sodium channel
title_sort	complete structure of an activated open sodium channel
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1
work_keys_str_mv	AT altinsula thecompletestructureofanactivatedopensodiumchannel AT jenniferbooker thecompletestructureofanactivatedopensodiumchannel AT leoctng thecompletestructureofanactivatedopensodiumchannel AT claireenaylor thecompletestructureofanactivatedopensodiumchannel AT paulgdecaen thecompletestructureofanactivatedopensodiumchannel AT bawallace thecompletestructureofanactivatedopensodiumchannel AT altinsula completestructureofanactivatedopensodiumchannel AT jenniferbooker completestructureofanactivatedopensodiumchannel AT leoctng completestructureofanactivatedopensodiumchannel AT claireenaylor completestructureofanactivatedopensodiumchannel AT paulgdecaen completestructureofanactivatedopensodiumchannel AT bawallace completestructureofanactivatedopensodiumchannel
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The complete structure of an activated open sodium channel

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