The complete structure of an activated open sodium channel
Voltage-gated sodium (Nav) channels are crucial for action potential initiation in excitable cells. Here the authors present the complete structure of prokaryotic NavMs in a fully open state, providing structural insight into the opening and closure of the channel's intracellular gate.
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Auteurs principaux: | Altin Sula, Jennifer Booker, Leo C. T. Ng, Claire E. Naylor, Paul G. DeCaen, B. A. Wallace |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/e9790fdf9aa34bac8509eea7e2e8e3c1 |
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