Kv1.1 channels mediate network excitability and feed-forward inhibition in local amygdala circuits

Abstract Kv1.1 containing potassium channels play crucial roles towards dampening neuronal excitability. Mice lacking Kv1.1 subunits (Kcna1 −/− ) display recurrent spontaneous seizures and often exhibit sudden unexpected death. Seizures in Kcna1 −/− mice resemble those in well-characterized models o...

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Autores principales: Samrat Thouta, Yiming Zhang, Esperanza Garcia, Terrance P. Snutch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e9bfc6bc7c2a4821a0c1e8709e0da20f
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