Kv1.1 channels mediate network excitability and feed-forward inhibition in local amygdala circuits
Abstract Kv1.1 containing potassium channels play crucial roles towards dampening neuronal excitability. Mice lacking Kv1.1 subunits (Kcna1 −/− ) display recurrent spontaneous seizures and often exhibit sudden unexpected death. Seizures in Kcna1 −/− mice resemble those in well-characterized models o...
Saved in:
Main Authors: | Samrat Thouta, Yiming Zhang, Esperanza Garcia, Terrance P. Snutch |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/e9bfc6bc7c2a4821a0c1e8709e0da20f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A forward genetic screen identifies Dolk as a regulator of startle magnitude through the potassium channel subunit Kv1.1.
by: Joy H Meserve, et al.
Published: (2021) -
The role of axonal Kv1 channels in CA3 pyramidal cell excitability
by: Sylvain Rama, et al.
Published: (2017) -
Balancing feed-forward excitation and inhibition via Hebbian inhibitory synaptic plasticity.
by: Yotam Luz, et al.
Published: (2012) -
Extracellular redox sensitivity of Kv1.2 potassium channels
by: Victoria A. Baronas, et al.
Published: (2017) -
A channelopathy mutation in the voltage-sensor discloses contributions of a conserved phenylalanine to gating properties of Kv1.1 channels and ataxia
by: Sonia Hasan, et al.
Published: (2017)