Immunomics-guided discovery of serum and urine antibodies for diagnosing urogenital schistosomiasis: a biomarker identification study

Summary: Background: Sensitive diagnostics are needed for effective management and surveillance of schistosomiasis so that current transmission interruption goals set by WHO can be achieved. We aimed to screen the Schistosoma haematobium secretome to find antibody biomarkers of schistosome infectio...

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Autores principales: Mark S Pearson, PhD, Bemnet A Tedla, PhD, Gebeyaw G Mekonnen, PhD, Carla Proietti, PhD, Luke Becker, BSc, Rie Nakajima, MSc, Al Jasinskas, PhD, Denise L Doolan, PhD, Abena S Amoah, PhD, Stefanie Knopp, PhD, David Rollinson, PhD, Said M Ali, MSc, Fatma Kabole, MD, Cornelis H Hokke, PhD, Akim A Adegnika, MD, Matt A Field, PhD, Govert van Dam, PhD, Paul L A M Corstjens, PhD, Takafira Mduluza, PhD, Francisca Mutapi, PhD, Claude Oeuvray, PhD, Beatrice Greco, PhD, Sujittra Chaiyadet, PhD, Thewarach Laha, PhD, Pengfei Cai, PhD, Donald P McManus, PhD, Maria Elena Bottazzi, PhD, Philip L Felgner, PhD, Javier Sotillo, PhD, Alex Loukas, PhD
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/e9c0510583ca4bf58360b82613221a36
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