Detection of cell-type-specific risk-CpG sites in epigenome-wide association studies

Cellular heterogeneity is one of the major confounding factors in EWAS studies. Here the authors present a statistical method, HIgh REsolution (HIRE), which enables the detection of risk-CpG sites for individual cell types.

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Detalles Bibliográficos
Autores principales: Xiangyu Luo, Can Yang, Yingying Wei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e9cc3f68adb44c948f64c6906ceaed6d
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