Model‐based assessments of CYP3A‐mediated drug‐drug interaction risk of milademetan
Abstract Milademetan is a small‐molecule inhibitor of murine double minute 2 (MDM2) that is in clinical development for advanced solid tumors and hematological cancers, including liposarcoma and acute myeloid leukemia. Milademetan is a CYP3A and P‐glycoprotein substrate and moderate CYP3A inhibitor....
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Wiley
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/e9cdb914f78a466084a85f5aa18226a3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|