Drug-specific Treg cells are induced during desensitization procedure for rituximab and tocilizumab in patients with anaphylaxis

Abstract Biologic agents (BA) are able to induce an adaptive immune response in a proportion of exposed patients with the onset of anti-drug antibodies (ADA), which are usually responsible for hypersensitivity reactions (HR). Drug desensitization (DD) for BA allows transient clinical tolerance to th...

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Autores principales: Alessandra Vultaggio, Francesca Nencini, Susanna Bormioli, Elena Silvestri, Laura Dies, Emanuele Vivarelli, Enrico Maggi, Andrea Matucci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e9e52b0688aa4ef3b1e3b6c04744234c
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