Angiotensin 1-7 and losartan worsen the cisplatin induced nephrotoxicity in female rats

Introduction: Cisplatin (CP) is an anti-cancer drug with the most common side effects of nephrotoxicity. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist and angiotensin 1-7 (Ang1-7) protects the kidney against CP administration in males Moreover, the activity of the renin angiotensin s...

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Main Authors: Sayyedehnikta Kasaei, Zahra Pezeshki, Farzaneh Karimi, Zahra Lak, Samira Choopani, Ardeshir Talebi, Mehdi Nematbakhsh
Format: article
Language:EN
Published: Society of Diabetic Nephropathy Prevention 2022
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Online Access:https://doaj.org/article/ea0645b4b1904d5093f609349facec66
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