Friedel–Crafts reaction of indoles for (3-indolyl)methyl ethers under basic condition: Application in unsymmetrical bis(indolyl)methanes

An efficient process to prepare (3-indolyl)methyl ethers from various indoles and benzaldehydes under basic conditions was reported. The effects of bases, solvents were investigated. Under the optimal condition, most of (3-indolyl)methyl ethers were obtained in 90–98% yields. The utility of the (3-i...

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Bibliographic Details
Main Authors: Zubiao Zheng, Daoxin Zha, Peng Cui, Huan Zhang, Changjiang Li, Jianjun Shi, Bingbing Han
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/ea3de14204cb40b68f2091db65b742a8
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